Abstract: This study focuses on a HBV model that is equipped with a new glacier module using the DEM data and simulates the glacier and snow melt runoff in the Kashi River basin, a branch of the Ili River in Xinjiang, based on its glacier inventory dataset and hydrometeorological data from 1990 to 2000 to reveal the variation trends in snowmelt in the alpine region. We found out that glaciers exist in the areas of elevation above 2695 m and concentrate on the elevation of 3195 - 3695 m. The model is calibrated for the period of 1990-1995 and verified for 1996-2000, and its simulations show a good agreement with the runoff measurements, achieving coefficients of determination and Nash-Sutcliffe efficiency coefficients of 0.86 and 0.83 for the calibration period and 0.83 and 0.80 for the validation period, respectively. Extreme value analysis reveals that in comparison with the measurements, absolute errors in the calculations of maximum and minimum runoffs fall in the range of 0.28 - 4.57 mm and 0.10 - 0.17 mm, respectively. The results show good applicability of the HBV model in the study area.