Abstract: To reduce sedimentation in the Ningxia-Inner Mongolia reaches of the upper Yellow, joint operation schemes of the Longyangxia and Liujiaxia cascade reservoirs were studied in this work to scour the river channel using artificial controlled floods. First, we analyzed the best time for regulating water and sediment and established a system of indexes to character the regulation. Then, a multi-objective operation model was developed and solved using a non-dominated sorting genetic algorithm (NSGA-II) to quantify the regulation effect in wet years or partial wet years. Third, four-dimensional vector coordinate systems were adopted to describe the objectives of the regulation schemes, and their sensitivity in different years was analyzed to clarify the impact of variables, such as controlled flow and water supply, on each objective. Lastly, transformation relationships among the objectives were revealed. The results are of great significance for implementing water and sediment regulation in the upper Yellow.